• A5 paper size, an ISO 216 international standard paper size (148×210 mm)
• A5 pod, a name given to a group of orcas (Orcinus orca) found off the coast of British Columbia, Canada
• A5 regulatory sequence in biochemistry
• Annexin A5, a human cellular protein
• ATC code A05 Bile and liver therapy, a subgroup of the Anatomical Therapeutic Chemical Classification System
• British NVC community A5 , a British Isles plants community
• Gibson A-5 mandolin, a Gibson mandolin
• Tippmann A-5, a semi-automatic pneumatic marker for playing paintball
• Subfamily A5, a Rhodopsin-like receptors subfamily
• In Town and country planning in the United Kingdom, A5 is the code for permission to use specific land or premises for takeaways
• A5 grade
• A5, an aid climbing gear manufacturer created by John Middendorf (absorbed by The North Face in 1997)
• A5/1, A5/2 and A5/3, ciphers used in cellular phones
• A05, Réti Opening Encyclopaedia of Chess Openings code
• Bhutan aircraft registration code

In transport

• Chery A5, a 2006 Chinese car
• Audi A5, a 2007 luxury coupé
• Arrows A5, a 1982 British racing car

• A5 road, in several countries

• Bavarian A V, a 1853 steam locomotive model
• Hall-Scott A-5, an engine powering the 1916 Standard H-2 aircraft
• Prussian A 5, a 1913 German railbus
• Route A5 , a bus route operated by the Washington Metropolitan Area Transit Authority
• Airlinair IATA code

In the military

• A-5 Fantan, an export version of Nanchang Q-5, a Chinese-built jet fighter bomber
• Curtiss Falcon or A-5 Falcon, an attack aircraft manufactured by the Curtiss Aircraft Company
• Mitsubishi A5M, a 1930s Japanese fighter plane
• A-5 Vigilante, a carrier-based supersonic bomber designed for the United States Navy
• Focke-Wulf A 5, a WWI German

• USS A-5 or USS Pike (SS-6), a 1903 United States Navy Plunger-class submarine
• HMS A5, an A-class submarine of the Royal Navy
• Aggregate series#A5, a German rocket design in World War II
• A 5, a Swedish regiment designation, according to the list of Swedish artillery regiments
• A5, the staff designation for air force headquarters staff concerned with plans or strategy
  • In the United Kingdom, the Joint Force Air Component Headquarters A5 - Air Strategy and GAT branch
• A5 Juggernaut, an armored fighting vehicle in the Star Wars fictional universe