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{{drugbox |
IUPAC_name = (E)-3-{6-[(E)-1-(4-methylphenyl)-3-pyrrolidin-1-yl-
prop-1-enyl]pyridin-2-yl}prop-2-enoic acid
image = Acrivastine.svg
CAS_number = 87848-99-5
ATC_prefix = R06
ATC_suffix = AX18
PubChem = 5284514
DrugBank =
H = 24 | N = 2 | O = 2
molecular_weight = 348.438 g/mol
smiles = CC1=CC=C(C=C1)C(=CCN2CCCC2)C3=CC=CC(=N3)C=CC(=O)O
bioavailability =
protein_bound =
metabolism =
elimination_half-life = 1.5 hours
excretion = Renal
pregnancy_AU =
pregnancy_US = B
legal_AU =
legal_CA =
legal_UK =
legal_US = Rx-only
legal_status =
routes_of_administration = oral}}Acrivastine is a medication used for the treatment of allergies and hay fever. It is a second-generation H1-receptor antagonist antihistamine and works by blocking H1 histamine receptors.

It is sold under the brand name Benadryl Allergy Relief in the U.K.marker by Pfizer, not to be confused with Benadryl Once a Day, which is cetirizine and is also sold by Pfizer in the U.K.This drug is currently not available as a generic in the U.K.

In the U.S., acrivastine is the active ingredient in the Semprex brand. Semprex-D is also acrivastine based, but contains a decongestant, pseudoephedrine. Semprex-D is marketed in the U.S. by UCB, Inc..


  1. Cheapest hayfever remedies 2007, Money Saving expert, May 15,2007
  2. [ Products - United States] UCB
  3. [ SEMPREX-D - acrivastine and pseudoephedrine hydrochloride capsule] U.S. National Library of Medicine, National Institutes of Health, Health & Human Services, May 2008

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