• Boyle , a lunar crater
• Boyle's law in physics, one of the gas laws; named after Irish natural philosopher Robert Boyle

Equipment

• Boyle's machine as used in the administration of general anaesthesia to patients

Places

• Boyle, Alberta, a village in Alberta, Canada
• Boyle, County Roscommon, in Ireland
• Boyle, Mississippi, in the United States of America

Surnames

• Alice Boyle, 17th-century Lady
• Brendan F. Boyle, Politician
• Buzz Boyle (1908-1978), Major League Baseball player
• Charles Boyle, 3rd Viscount Dungarvan
• Charles P. Goyle, American cinematographer
• Dan Boyle , professional ice hockey player
• Danny Boyle, British film director, cousin of John Wayne
• David Boyle
• Eddie Boyle (1874-1941), Major League Baseball player
• Emmet D. Boyle, former Governor of Nevada
• Greg Boyle, S.J., Jesuit priest in East Los Angeles
• Frankie Boyle, Scottish comedian
• Henry Edmund Gaskin Boyle, anaesthesiologist
• Jack Boyle (1866-1913), Major League Baseball player
• James Boyle
• Jeremiah Boyle, Union Brigadier General during the American Civil War
• Jim Boyle, Ohio politician
• Joan Boyle
• Joseph W. Boyle, Canadian adventurer
• Katie Boyle, television presenter
• Kay Boyle, U.S. writer and political activist
• Lara Flynn Boyle, U.S. actress
• Lisa Boyle, U.S. model
• Lettice Boyle, 17th-century Lady
• Mary Boyle, Countess of Cork and Orrery, 18th-century British literary hostess
• Mike Boyle, Mayor, Omaha, NE
• Nicholas Boyle, British literature historian
• Peter Boyle, U.S. actor, 1935-2006
• Phelim Boyle, quantitative finance academic
• Richard Boyle, 1st Earl of Cork, former Lord High Treasurer of the Kingdom of Ireland circa 1600's
• Richard Boyle, 1st Earl of Burlington
• Robert Boyle, Irish natural philosopher
• Robert William Boyle, Canadian physicist, co-inventor of sonar
• Roger Boyle, first Earl of Orrery
• Ruth-Ann Boyle, singer of the British group Olive
• Sarah Boyle, Irish 17th-century Lady
• Susan Boyle, Scottish singer and a contestant on the 3rd series of Britain's Got Talent
• T. Coraghessan Boyle, U.S. novelist and short story writer
• Troy Boyle, U.S. comic book artist and writer