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Friderik “Fritz” Pregl (3 September 1869 – 13 December 1930) was an Austria chemist and physician from a mixed Slovene-German-speaking background. He won the Nobel Prize in Chemistry in 1923 for making important contributions to quantitative organic microanalysis, one of which was the improvement of the combustion train technique for elemental analysis.


Pregl was born in Ljubljanamarker within Austria-Hungary to a Slovene-speaking father and German-speaking mother. He died in Grazmarker, Austriamarker in 1930.

Pregl started his career as physician after he studied medicine at the University of Grazmarker. With his focus on physiology and especially chemical physiology, he suffered from the limitations of quantitative organic microanalysis. The small quantities of substances he obtained during the research of Bile acid made it necessary improve the process of elemental analysis by reducing the necessary components. At the end of his research, he had lowered the minimal amount of substance necessary for the analysis process by a factor of 50. He invited chemists to learn his method of elemental analysis, so that the method was soon widely accepted.


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