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HLA-B44: Map

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HLA-B (alpha)-β2MG with bound peptide
major histocompatibility complex (human), class I, B44
Alleles B*4401, 4402, 4403 . .
Structure (See HLA-B)
Shared data
Locus chr.6 6p21.31
HLA-B44 (B44) is an HLA-B serotype. The serotype identifies the B*44 gene-allele protein products of HLA-B.

B44 is a split antigen of the broad antigen B12, and is a sister type of B45.

Serotype

Serotypes B44, B12, and B45 recognition of the HLA B*44 gene products
B*44 B44 B12 B45 Sample
allele % % % size (N)
98 6959
94 2854
65 42
92 130
44 9
B*4401 was shown to be B*4402 after errors corrected.
Alleles link-out to IMGT/HLA Databease at EBImarker





Alleles

Disease

HLA-B44 increases recurrent sinopulmonary infections. Protective effects: HLA-B44 appears to be protective against autoimmune lymphoproliferative syndrome in patients with C95 defect (ALPS type Ia). B44 may be a cofactor in ankylosing spondylitis

References

  1. derived from IMGT/HLA



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