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Lodenafil is a drug belonging to a class of drugs called PDE5 inhibitor, which many other erectile dysfunction drugs such as sildenafil, tadalafil, and vardenafil also belong to. Like udenafil and avanafil it belongs to a new generation of PDE5 inhibitors.

It is manufactured by Cristália Produtos Químicos e Farmacêuticos in Brazilmarker and sold there under the brand-name Helleva® .

It has undergone Phase II clinical trials and is not yet approved for use in the United Statesmarker by the U.S. Food and Drug Administration.

Further clinical trials are being conducted .

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