The "Nutrition Facts" table indicates the amounts of nutrients
which experts recommend you limit or consume in adequate
amounts.
Nutrition (also called
nourishment or
aliment) is the
provision, to
cells and
organisms, of the materials necessary (in the form
of food) to support
life. Many common health
problems can be prevented or alleviated with a
healthy diet.
The
diet of an organism is what it
eats, and is largely determined by the perceived
palatability of foods.
Dietitians are
health professionals who specialize in
human nutrition, meal planning, economics, and preparation. They
are trained to provide safe, evidence-based dietary advice and
management to individuals (in health and disease), as well as to
institutions.
A poor diet can have an injurious impact on health, causing
deficiency diseases such as
scurvy,
beriberi, and
kwashiorkor; health-threatening conditions like
obesity and
metabolic syndrome, and such common
chronic systemic diseases as
cardiovascular disease,
diabetes, and
osteoporosis.
Overview
Nutritional science investigates the
metabolic and physiological responses of the body
to diet. With advances in the fields of
molecular biology,
biochemistry, and
genetics, the study of nutrition is increasingly
concernedwith metabolism and
metabolic
pathways: the sequences of biochemical steps through which
substances in living things change from one form to another.
The
human body contains
chemical compounds, such as
water,
carbohydrates
(sugar, starch, and
fiber),
amino acids (in
proteins),
fatty acids
(in
lipids), and
nucleic acids (
DNA and
RNA). These compounds in turn consist of
elements such as
carbon,
hydrogen,
oxygen,
nitrogen,
phosphorus,
calcium,
iron,
zinc,
magnesium,
manganese, and
so on. All of these chemical compounds and elements occur in
various forms and combinations (e.g.
hormones,
vitamins,
phospholipids,
hydroxyapatite), both in the
human body and in the plant and animal organisms
that humans eat.
The human body consists of elements and compounds ingested,
digested, absorbed, and circulated through the
bloodstream to feed the
cell of the body. Except in the unborn fetus,
the
digestive system is the first
system involved . In a typical adult, about seven liters of
digestive juices enter the
lumen of
the digestive tract. These break
chemical
bonds in ingested molecules, and modulate their
conformation and energy states. Though
some molecules are absorbed into the bloodstream unchanged,
digestive processes release them from the matrix of foods.
Unabsorbed matter, along with some waste products of
metabolism, is eliminated from the body in the
feces.
Studies of nutritional status must take into account the state of
the body before and after experiments, as well as the
chemical composition of the whole diet and of all
material
excreted and eliminated from the
body (in
urine and feces). Comparing the food
to the waste can help determine the specific compounds and elements
absorbed and metabolized in the body. The effects of nutrients may
only be discernible over an extended period, during which all food
and waste must be analyzed. The number of
variables involved in such
experiments is high, making nutritional studies
time-consuming and expensive, which explains why the science of
human nutrition is still slowly evolving.
In general, eating a wide variety of fresh, whole (unprocessed),
foods has proven favorable compared to monotonous diets based on
processed foods. In particular, the consumption of whole-plant
foods slows digestion and allows better absorption, and a more
favorable balance of essential nutrients per
Calorie, resulting in better management of cell
growth, maintenance, and
mitosis (cell
division), as well as better regulation of appetite and blood sugar
. Regularly scheduled meals (every few hours) have also proven more
wholesome than infrequent or haphazard ones.
Nutrients
There are seven major classes of nutrients:
carbohydrates,
fats,
fiber,
minerals,
protein,
vitamin, and
water.
These nutrient classes can be categorized as either
macronutrients (needed in relatively large
amounts) or
micronutrients (needed in
smaller quantities). The macronutrients are carbohydrates, fats,
fiber, proteins, and water. The micronutrients are minerals and
vitamins.
The macronutrients (excluding fiber and water) provide structural
material (amino acids from which proteins are built, and lipids
from which cell membranes and some signaling molecules are built),
energy. Some of the structural
material can be used to generate energy internally, and in either
case it is measured in
Joules or
kilocalories (often called "Calories" and written
with a capital
C to distinguish them from little 'c'
calories). Carbohydrates and proteins provide 17 kJ
approximately (4 kcal) of energy per gram, while fats provide
37 kJ (9 kcal) per gram., though the net energy from
either depends on such factors as absorption and digestive effort,
which vary substantially from instance to instance. Vitamins,
minerals, fiber, and water do not provide energy, but are required
for other reasons. A third class dietary material, fiber (ie,
non-digestible material such as cellulose), seems also to be
required, for both mechanical and biochemical reasons, though the
exact reasons remain unclear.
Molecules of carbohydrates and fats consist of carbon, hydrogen,
and oxygen atoms. Carbohydrates range from simple
monosaccharides (glucose, fructose,
galactose) to complex
polysaccharides (starch). Fats are
triglycerides, made of assorted
fatty acid monomers bound
to
glycerol backbone. Some fatty acids, but
not all, are
essential in the
diet: they cannot be synthesized in the body. Protein molecules
contain nitrogen atoms in addition to carbon, oxygen, and hydrogen.
The fundamental components of protein are nitrogen-containing
amino acids, some of which are
essential in the sense that humans
cannot make them internally. Some of the amino acids are
convertible (with the expenditure of energy) to glucose and can be
used for energy production just as ordinary glucose. By breaking
down existing protein, some glucose can be produced internally; the
remaining amino acids are discarded, primarily as urea in urine.
This occurs normally only during prolonged starvation.
Other micronutrients include
antioxidants and
phytochemicals which are said to influence
(or protect) some body systems. Their necessity is not as well
established as in the case of, for instance, vitamins.
Most foods contain a mix of some or all of the nutrient classes,
together with other substances such as toxins or various sorts.
Some nutrients can be stored internally (eg, the fat soluble
vitamins), while others are required more or less continuously.
Poor health can be caused by a lack of required nutrients or, in
extreme cases, too much of a required nutrient. For example, both
salt and water (both absolutely required) will cause illness or
even death in too large amounts.
Carbohydrates

Toasted bread is a cheap, high calorie
nutrient (usually unbalanced, i.e., deficient in essential minerals
and vitamins, largely because of removal of both germ and bran
during processing) food source.
Carbohydrates may be classified as monosaccharides, disaccharides,
or polysaccharides depending on the number of monomer (sugar) units
they contain. They constitute a large part of foods such as
rice,
noodles,
bread, and other
grain-based
products.Monosaccharides contain one sugar unit, disaccharides two,
and polysaccharides three or more. Polysaccharides are often
referred to as
complex carbohydrates because they are
typically long multiple branched chains of sugar units. The
difference is that complex carbohydrates take longer to digest and
absorb since their sugar units must be separated from the chain
before absorption. The spike in blood glucose levels after
ingestion of simple sugars is thought to be related to some of the
heart and vascular diseases which have become more frequent in
recent times. Simple sugars form a greater part of modern diets
than formerly, perhaps leading to more cardiovascular disease. The
degree of causation is still not clear, however.
Simple carbohydrates are absorbed quickly, and therefore raise
blood-sugar levels more rapidly than other nutrients. However, the
most important plant carbohydrate nutrient, starch, varies in its
absorption. Gelatinized starch (starch heated for a few minutes in
the presence of water) is far more digestible than plain starch.
And starch which has been divided into fine particles is also more
absorbable during digestion. The increased effort and decreased
availability reduces the available energy from starchy foods
substantially and can be seen experimentally in rats and
anecdotally in humans. Additionally, up to a third of dietary
starch may be unavailable due to mechanical or chemical
difficulty.
Fat
A molecule of dietary fat typically consists of several
fatty acids (containing long chains of carbon and
hydrogen atoms), bonded to a
glycerol. They
are typically found as
triglycerides
(three fatty acids attached to one glycerol backbone). Fats may be
classified as
saturated or
unsaturated depending on the detailed
structure of the fatty acids involved. Saturated fats have all of
the carbon atoms in their fatty acid chains bonded to hydrogen
atoms, whereas unsaturated fats have some of these carbon atoms
double-bonded, so their molecules have
relatively fewer hydrogen atoms than a saturated fatty acid of the
same length. Unsaturated fats may be further classified as
monounsaturated (one double-bond) or polyunsaturated (many
double-bonds). Furthermore, depending on the location of the
double-bond in the fatty acid chain, unsaturated fatty acids are
classified as
omega-3 or
omega-6 fatty acids.
Trans
fats are a type of unsaturated fat with
trans-isomer
bonds; these are rare in nature and in foods from natural sources;
they are typically created in an industrial process called
(partial)
hydrogenation.
Many studies have shown that unsaturated fats, particularly
monounsaturated fats, are best in the human diet. Saturated fats,
typically from animal sources, are next, while trans fats are to be
avoided. Saturated and some trans fats are typically solid at room
temperature (such as
butter or
lard), while unsaturated fats are typically liquids
(such as
olive oil or
flaxseed oil). Trans fats are very rare in
nature, but have properties useful in the
food processing industry, such as rancid
resistance.
Essential fatty acids
Most fatty acids are non-essential, meaning the body can produce
them as needed, generally from other fatty acids and always by
expending energy to do so. However, in humans at least two fatty
acids are
essential and must
be included in the diet. An appropriate balance of essential fatty
acids -—
omega-3 and
omega-6 fatty acids -— seems also
important for health, though definitive experimental demonstration
has been elusive. Both of these "omega" long-chain
polyunsaturated fatty acids are
substrates for a class of
eicosanoids known as
prostaglandins, which have roles throughout
the human body. They are
hormones, in some
respects. The omega-3
eicosapentaenoic acid (EPA), which can
be made in the human body from the omega-3 essential fatty acid
alpha-linolenic acid (LNA), or
taken in through marine food sources, serves as a building block
for series 3 prostaglandins (e.g. weakly
inflammatory PGE3). The omega-6
dihomo-gamma-linolenic acid (DGLA) serves as a building block for
series 1 prostaglandins (e.g. anti-inflammatory PGE1), whereas
arachidonic acid (AA) serves as a building block for series 2
prostaglandins (e.g. pro-inflammatory PGE 2). Both DGLA and AA can
be made from the omega-6
linoleic acid
(LA) in the human body, or can be taken in directly through food.
An appropriately balanced intake of omega-3 and omega-6 partly
determines the relative production of different prostaglandins: one
reason a balance between omega-3 and omega-6 is believed important
for cardiovascular health. In industrialized societies, people
typically consume large amounts of processed vegetable oils, which
have reduced amounts of the essential fatty acids along with too
much of omega-6 fatty acids relative to omega-3 fatty acids.
The conversion rate of omega-6 DGLA to AA largely determines the
production of the prostaglandins PGE1 and PGE2. Omega-3 EPA
prevents AA from being released from membranes, thereby skewing
prostaglandin balance away from pro-inflammatory PGE2 (made from
AA) toward anti-inflammatory PGE1 (made from DGLA). Moreover, the
conversion (desaturation) of DGLA to AA is controlled by the enzyme
delta-5-desaturase, which in turn is
controlled by hormones such as
insulin
(up-regulation) and
glucagon
(down-regulation). The amount and type of carbohydrates consumed,
along with some types of amino acid, can influence processes
involving insulin, glucagon, and other hormones; therefore the
ratio of omega-3 versus omega-6 has wide effects on general health,
and specific effects on immune function and
inflammation, and
mitosis (i.e. cell division).
Good sources of essential fatty acids include most vegetables,
nut, seeds, and marine oils, Some of the
best sources are
fish,
flax seed oils,
soy beans,
pumpkin seeds,
sunflower seeds, and
walnuts.
Fiber
Dietary fiber is a
carbohydrate (or a
polysaccharide) that is incompletely absorbed in humans and in some
animals. Like all carbohydrates, when it is metabolized it can
produce four calories (kilocalories) of energy per gram. But in
most circumstances it accounts for less than that because of its
limited absorption and digestibility. Dietary fiber consists mainly
of
cellulose, a large carbohydrate polymer
that is indigestible because humans do not have the required
enzymes to disassemble it. There are two subcategories: soluble and
insoluble fiber. Whole grains, fruits (especially
plums,
prunes, and
figs), and vegetables are good sources of dietary fiber.
Fiber is important to digestive health and is thought to reduce the
risk of colon cancer. For mechanical reasons it can help in
alleviating both
constipation and
diarrhea. Fiber provides bulk to the
intestinal contents, and insoluble fiber especially stimulates
peristalsis -- the rhythmic muscular
contractions of the intestines which move digesta along the
digestive tract. Some soluble fibers produce a solution of high
viscosity; this is essentially a gel,
which slows the movement of food through the intestines.
Additionally, fiber, perhaps especially that from whole grains, may
help lessen insulin spikes and reduce the risk of type 2
diabetes.
Protein
Proteins are the basis of many animal body structures (e.g.
muscles, skin, and hair). They also form the enyzmes which control
chemical reactions throughout the body. Each molecule is composed
of
amino acids which are characterized
by inclusion of nitrogen and sometimes sulphur (these components
are responsible for the distinctive smell of burning protein, such
as the keratin in hair). The body requires amino acids to produce
new proteins (protein retention) and to replace damaged proteins
(maintenance). As there is no protein or amino acid storage
provision, amino acids must be present in the diet. Excess amino
acids are discarded, typically in the urine. For all animals, some
amino acids are
essential (an animal cannot
produce them internally) and some are
non-essential (the animal can
produce them from other nitrogen-containing compounds). About
twenty amino acids are found in the human body, and about ten of
these are essential, and therefore must be included in the diet. A
diet that contains adequate amounts of amino acids (especially
those that are essential) is particularly important in some
situations: during early development and maturation, pregnancy,
lactation, or injury (a burn, for instance). A
complete
protein source contains all the essential amino acids; an
incomplete protein source lacks one or more of the
essential amino acids.
It is possible to combine two incomplete protein sources (e.g. rice
and beans) to make a complete protein source, and characteristic
combinations are the basis of distinct cultural cooking traditions.
Sources of dietary protein include
meats,
tofu and other
soy-products,
eggs,
grains,
legumes, and
dairy
products such as
milk and
cheese. A few amino acids from protein can be
converted into glucose and used for fuel through a process called
gluconeogenesis; this is done in
quantity only during starvation. The amino acids remaining after
such conversion are discarded.
Minerals
Dietary minerals are the
chemical
elements required by living organisms, other than the four
elements
carbon,
hydrogen,
nitrogen, and
oxygen that are present in nearly all
organic molecules. The term
"mineral" is archaic, since the intent is to describe simply the
less common elements in the diet. Some are heavier than the four
just mentioned—including several
metals,
which often occur as ions in the body. Some dietitians recommend
that these be supplied from foods in which they occur naturally, or
at least as complex compounds, or sometimes even from natural
inorganic sources (such as
calcium
carbonate from ground
oyster shells).
Some are absorbed much more readily in the ionic forms found in
such sources. On the other hand, minerals are often artificially
added to the diet as supplements; the most famous is likely iodine
in
iodized salt which prevents
goiter.
Macrominerals
Many elements are essential in relative quantity; they are usually
called "bulk minerals". Some are structural, but many play a role
as
electrolytes. Elements with
recommended dietary allowance (
RDA) greater than
200 mg/day are, in alphabetical order (with informal or
folk-medicine perspectives in parentheses):
- Calcium, a common electrolyte, but also
needed structurally structural (for muscle and digestive system
health, bones, some forms neutralizes acidity, may help clear
toxins, and provide signaling ions for nerve and membrane
functions
- Chlorine as chloride ions; very common electrolyte; see sodium,
below
- Magnesium, required for processing
ATP and related reactions
(builds bone, causes strong peristalsis, increases flexibility,
increases alkalinity)
- Phosphorus, required component of
bones; essential for energy processing
- Potassium, a very common electrolyte
(heart and nerve health)
- Sodium, a very common electrolyte; not
generally found in dietary supplements, despite being needed in
large quantities, because the ion is very common in food: typically
as sodium chloride, or common
salt
- Sulfur for three essential amino acids
and therefore many proteins (skin, hair, nails, liver, and
pancreas)
Trace minerals
Many elements are required in trace amounts, usually because they
play a
catalytic role in
enzymes. Some trace mineral elements (RDA
200 mg/day) are, in alphabetical order:
- Cobalt required for biosynthesis of
vitamin B12 family of coenzymes
- Copper required component of many redox
enzymes, including cytochrome c
oxidase
- Chromium required for sugar
metabolism
- Iodine required not only for the
biosynthesis of thyroxin, but probably, for
other important organs as breast, stomach, salivary glands, thymus
etc. (see Extrathyroidal iodine); for this
reason iodine is needed in larger quantities than others in this
list, and sometimes classified with the macrominerals
- Iron required for many enzymes, and for
hemoglobin and some other proteins
- Manganese (processing of oxygen)
- Molybdenum required for xanthine oxidase and related oxidases
- Nickel present in urease
- Selenium required for peroxidase (antioxidant proteins)
- Vanadium (Speculative: there is no
established RDA for vanadium. No specific biochemical function has
been identified for it in humans, although vanadium is required for
some lower organisms.)
- Zinc required for several enzymes such as
carboxypeptidase, liver alcohol dehydrogenase,
carbonic anhydrase
Vitamins
As with the minerals discussed above, some vitamins are recognized
as essential nutrients, necessary in the diet for good health.
(
Vitamin D is the exception: it can
alternatively be synthesized in the skin, in the presence of
UVB radiation.) Certain vitamin-like
compounds that are recommended in the diet, such as
carnitine, are thought useful for survival and
health, but these are not "essential" dietary nutrients because the
human body has some capacity to produce them from other compounds.
Moreover, thousands of different
phytochemicals have recently been discovered
in food (particularly in fresh vegetables), which may have
desirable properties including
antioxidant activity (see below); experimental
demonstration has been suggestive but inconclusive. Other essential
nutrients not classed as vitamins include
essential amino acids (see
above),
choline,
essential fatty acids (see
above), and the minerals discussed in
the preceding section.
Vitamin deficiencies may result in disease conditions:
goitre,
scurvy,
osteoporosis, impaired
immune system, disorders of cell
metabolism, certain forms of cancer, symptoms of
premature
aging, and poor
psychological health (including
eating disorders), among many others.
Excess of some vitamins is also dangerous to health (notably
vitamin A), and for at least one vitamin,
B6, toxicity begins at levels not far above the required
amount.Deficiency or excess of minerals can also have serious
health consequences.
Water
About 70% of the non-fat mass of the
human
body is made of water. To function properly, the body requires
between one and seven
liters of water per
day to avoid
dehydration; the precise amount depends on the
level of activity, temperature, humidity, and other factors. With
physical exertion and heat exposure, water loss increases and daily
fluid needs will eventually increase as well.
It is not fully clear how much water intake is needed by healthy
people, although some experts assert that 8–10 glasses of water
(approximately 2 liters) daily is the minimum to maintain proper
hydration. The notion that a person should consume eight glasses of
water per day cannot be traced to a credible scientific source. The
effect of, greater or lesser, water intake on weight loss and on
constipation is also still unclear. The original water intake
recommendation in 1945 by the
Food and Nutrition Board of the
National
Research Council read: "An ordinary standard for diverse
persons is 1 milliliter for each calorie of food. Most of this
quantity is contained in prepared foods." The latest dietary
reference intake report by the
United States National
Research Council recommended, generally, (including food
sources): 2.7 liters of water total for women and 3.7 liters for
men. Specifically,
pregnant and
breastfeeding women need additional fluids to
stay hydrated. According to the
Institute of Medicine—who recommend
that, on average, women consume 2.2 litres and men 3.0 litres—this
is recommended to be 2.4 litres (approx. 9 cups) for pregnant women
and 3 litres (approx. 12.5 cups) for breastfeeding women since an
especially large amount of fluid is lost during nursing.
For those who have healthy kidneys, it is somewhat difficult to
drink too much water, but (especially in warm humid weather and
while exercising) it is dangerous to drink too little. People can
drink far more water than necessary while exercising, however,
putting them at risk of
water
intoxication, which can be fatal. In particular large amounts
of de-ionized water are dangerous.
Normally, about 20 percent of water intake comes in food, while the
rest comes from drinking water and assorted beverages (
caffeinated included). Water is excreted from the
body in multiple forms; including
urine and
feces,
sweating, and by
water vapor in the exhaled breath.
Other nutrients
Other micronutrients include antioxidants and phytochemicals. These
substances are generally more recent discoveries which have not yet
been recognized as vitamins or as required. Phytochemicals may act
as antioxidants, but not all phytochemicals are antioxidants.
Antioxidants
Antioxidants are a recent discovery. As cellular
metabolism/energy production requires oxygen,
potentially damaging (e.g.
mutation
causing) compounds known as
free
radicals can form. Most of these are oxidizers (i.e. acceptors
of electrons) and some react very strongly. For normal cellular
maintenance, growth, and division, these free radicals must be
sufficiently neutralized by antioxidant compounds. Recently, some
researchers suggested an interesting theory of
evolution of dietary
antioxidants. Some are produced by the human body with adequate
precursors (
glutathione,
Vitamin C)
and those the body cannot produce may only be obtained in the diet
via direct sources (Vitamin C in humans,
Vitamin A,
Vitamin K) or
produced by the body from other compounds (
Beta-carotene converted to Vitamin A by the
body,
Vitamin D synthesized from
cholesterol by
sunlight). Phytochemicals (
Section Below)
and their subgroup polyphenols are the majority of antioxidants;
about 4,000 are known. Different antioxidants are now known to
function in a cooperative network, e.g. vitamin C can reactivate
free radical-containing
glutathione or
vitamin E by accepting the free radical itself, and so on. Some
antioxidants are more effective than others at neutralizing
different free radicals. Some cannot neutralize certain free
radicals. Some cannot be present in certain areas of free radical
development (Vitamin A is
fat-soluble
and protects fat areas, Vitamin C is
water
soluble and protects those areas). When interacting with a free
radical, some antioxidants produce a different free radical
compound that is less dangerous or more dangerous than the previous
compound. Having a variety of antioxidants allows any byproducts to
be safely dealt with by more efficient antioxidants in neutralizing
a free radical's
butterfly
effect.
Phytochemicals
A growing area of interest is the effect upon human health of trace
chemicals, collectively called
phytochemicals. These nutrients are typically
found in edible plants, especially colorful fruits and vegetables,
but also other organisms including seafood, algae, and fungi. The
effects of phytochemicals increasingly survive rigorous testing by
prominent health organizations. One of the principal classes of
phytochemicals are
polyphenol
antioxidants, chemicals which are known to provide certain
health benefits to the
cardiovascular system and
immune system. These chemicals are known to
down-regulate the formation of
reactive oxygen species, key
chemicals in
cardiovascular
disease.
Perhaps the most rigorously tested phytochemical is
zeaxanthin, a yellow-pigmented carotenoid present
in many yellow and orange fruits and vegetables. Repeated studies
have shown a strong correlation between ingestion of zeaxanthin and
the prevention and treatment of
age-related macular
degeneration (AMD). Less rigorous studies have proposed a
correlation between zeaxanthin intake and
cataracts.
A second carotenoid, lutein, has also been shown to lower the risk
of contracting AMD. Both compounds have been observed to collect in
the retina when ingested orally, and they serve to protect the rods
and cones against the destructive effects of light.
Another carotenoid, beta-
cryptoxanthin, appears to protect against
chronic joint inflammatory diseases, such as
arthritis. While the association between serum
blood levels of beta-cryptoxanthin and substantially decreased
joint disease has been established, neither a convincing mechanism
for such protection nor a cause-and-effect have been rigorously
studied.
Am J Epidemiology 2006 163(1). Similarly, a red phytochemical,
lycopene, has substantial credible evidence
of negative association with development of prostate cancer.
The correlations between the ingestion of some phytochemicals and
the prevention of disease are, in some cases, enormous in
magnitude.
Even when the evidence is obtained, translating it to practical
dietary advice can be difficult and counter-intuitive. Lutein, for
example, occurs in many yellow and orange fruits and vegetables and
protects the eyes against various diseases. However, it does not
protect the eye nearly as well as zeaxanthin, and the presence of
lutein in the retina will prevent zeaxanthin uptake. Additionally,
evidence has shown that the lutein present in egg yolk is more
readily absorbed than the lutein from vegetable sources, possibly
because of fat solubility. At the most basic level, the question
"should you eat eggs?" is complex to the point of dismay, including
misperceptions about the health effects of cholesterol in egg yolk,
and its saturated fat content.
As another example, lycopene is prevalent in tomatoes (and actually
is the chemical that gives tomatoes their red color). It is more
highly concentrated, however, in processed tomato products such as
commercial pasta sauce, or
tomato soup,
than in fresh "healthy" tomatoes. Yet, such sauces tend to have
high amounts of salt, sugar, other substances a person may wish or
even need to avoid.
The following table presents phytochemical groups and common
sources, arranged by family:
| Family |
Sources |
Possible Benefits |
| flavonoids |
berries, herbs,
vegetables, wine,
grapes, tea |
general antioxidant, oxidation of
LDLs, prevention of arteriosclerosis and heart disease |
| isoflavones (phytoestrogens) |
soy, red clover,
kudzu root |
general antioxidant, prevention of
arteriosclerosis and heart disease, easing symptoms of menopause, cancer
prevention |
| isothiocyanates |
cruciferous
vegetables |
cancer prevention |
| monoterpenes |
citrus peels, essential oils, herbs,
spices, green
plants, atmosphere |
cancer prevention, treating gallstones |
| organosulfur
compounds |
chives, garlic,
onions |
cancer prevention, lowered LDLs, assistance to the immune
system |
| saponins |
beans, cereals,
herbs |
Hypercholesterolemia,
Hyperglycemia, Antioxidant, cancer
prevention,Anti-inflammatory |
| capsaicinoids |
all capiscum peppers |
topical pain relief, cancer prevention, cancer cell apoptosis |
Ash
Though not really a nutrient as such, an entry for
ash is
sometimes found on nutrition labels, especially for
pet food. This entry measures the weight of
inorganic material left over after the food is burned for two hours
at 600°C. Thus, it does not include water, fibre, and nutrients
that provide calories, but it does include some nutrients, such as
minerals
There have been some concerns that too much ash may contribute to
feline urological
syndrome in
domestic cats.
Intestinal bacterial flora
It is now also known that animal
intestines contain a large population of
gut flora. In humans, these include species such
as
Bacteroides,
L. acidophilus and
E. coli, among many others. They are essential
to
digestion, and are also affected by the
food we eat. Bacteria in the gut perform many important functions
for humans, including breaking down and aiding in the absorption of
otherwise indigestible food; stimulating cell growth; repressing
the growth of harmful bacteria, training the immune system to
respond only to pathogens; producing
vitamin
B12, and defending against some infectious diseases.
Advice and guidance
Governmental policies
In the US,
dietitians are registered (RD)
or licensed (LD) with the Commission for Dietetic Registration and
the American Dietetic Association, and are only able to use the
title "dietitian," as described by the business and professions
codes of each respective state, when they have met specific
educational and experiential prerequisites and passed a national
registration or licensure examination, respectively. In California,
registered dietitians must abide by the Anyone may call themselves
a nutritionist, including unqualified dietitians, as this term is
unregulated. Some states, such as the State of Florida, have begun
to include the title "nutritionist" in state licensure
requirements. Most governments provide guidance on nutrition, and
some also impose
mandatory
disclosure/labeling requirements for processed food
manufacturers and restaurants to assist consumers in complying with
such guidance.
In the US,
nutritional standards and recommendations are established jointly
by the US Department of
Agriculture
and US Department of Health and
Human Services. Dietary and physical activity guidelines
from the USDA are presented in the concept of a
food pyramid, which superseded the
Four Food Groups. The Senate committee
currently responsible for oversight of the USDA is the
Agriculture, Nutrition and Forestry Committee. Committee
hearings are often televised on
C-SPAN as
seen here.
The
U.S. Department of
Health and Human Services provides a sample week-long menu
which fulfills the nutritional recommendations of the government.
Canada's Food Guide is another
governmental recommendation.
Teaching
Nutrition is
taught in schools in many
countries. In
England and Wales
the
Personal and Social
Education and Food Technology curricula include nutrition,
stressing the importance of a balanced diet and teaching how to
read nutrition labels on packaging. In many schools a Nutrition
class will fall within the Family and Consumer Science or Health
departments. In some American schools, students are required to
take a certain number of FCS or Health related classes. Nutrition
is offered at many schools, and if it is not a class of its own,
nutrition is included in other FCS or Health classes such as: Life
Skills, Independent Living, Single Survival, Freshmen Connection,
Health etc. In many Nutrition classes, students learn about the
food groups, the food pyramid, Daily Recommended Allowances,
calories, vitamins, minerals, malnutrition, physical activity,
healthy food choices and how to live a healthy life.
A 1985 US
National Research
Council report entitled
Nutrition Education in US Medical
Schools concluded that nutrition education in medical schools
was inadequate. Only 20% of the schools surveyed taught nutrition
as a separate, required course. A 2006 survey found that this
number had risen to 30%.
Healthy diets
Whole plant food diet
Heart disease, cancer, obesity, and diabetes are commonly called
"Western" diseases because these maladies were once rarely seen in
developing countries.
One study in
China found some regions had essentially no cancer or heart
disease, while in other areas they reflected "up to a 100-fold
increase" coincident with diets that were found to be entirely
plant-based to heavily animal-based, respectively. In contrast,
diseases of affluence like cancer and heart disease are common
throughout the United States. Adjusted for age and exercise, large
regional clusters of people in China rarely suffered from these
"Western" diseases possibly because their diets are rich in
vegetables, fruits and whole grains.
The United Healthcare/Pacificare nutrition guideline recommends a
whole plant food diet, and recommends using protein only as a
condiment with meals.
A National Geographic
cover article from November, 2005, entitled
The Secrets of Living Longer, also recommends a whole
plant food diet. The article is a lifestyle survey of three
populations, Sardinians, Okinawans
, and Adventist, who generally
display longevity and "suffer a fraction of the diseases that
commonly kill people in other parts of the developed world, and
enjoy more healthy years of life." In sum, they offer three
sets of 'best practices' to emulate. The rest is up to you. In
common with all three groups is to "Eat fruits, vegetables, and
whole grains."
The
National Geographic article noted that an NIH
funded study
of 34,000 Seventh-day
Adventist between 1976 and 1988 "…found that the Adventists'
habit of consuming beans, soy milk, tomatoes, and other fruits
lowered their risk of developing certain cancers. It also
suggested that eating whole grain bread, drinking five glasses of
water a day, and, most surprisingly, consuming four servings of
nuts a week reduced their risk of heart disease."
The French "paradox"
It has been discovered that people living in France live longer.
Even though they consume more saturated fats than Americans, the
rate of heart disease is lower in France than in North America. A
number of explanations have been suggested:
- Reduced consumption of processed carbohydrate and other junk
foods.
- Regular consumption of red wine.
- More active lifestyles involving plenty of daily exercise,
especially walking; the French are much less dependent on cars than
Americans are.
- Higher consumption of artificially produced trans-fats by
Americans, which has been shown to have greater lipoprotein effects per gram than saturated
fat.
However, statistics collected by the
World Health Organization from
1990-2000 show that the incidence of heart disease in France may
have been underestimated and in fact be similar to that of
neighboring countries.
Sports nutrition
Protein
Protein is an important component of every cell in the body. Hair
and nails are mostly made of protein. The body uses protein to
build and repair tissues. Also protein is used to make enzymes,
hormones, and other body chemicals. Protein is an important
building block of bones, muscles, cartilage, skin, and blood.
The protein requirement for each individual differs, as do opinions
about whether and to what extent physically active people require
more protein. The 2005
Recommended Dietary Allowances
(RDA), aimed at the general healthy adult population, provide for
an intake of 0.8 - 1 grams of protein per kilogram of body weight
(according to the BMI formula), with the review panel stating that
"no additional dietary protein is suggested for healthy adults
undertaking resistance or endurance exercise". Conversely,
Di Pasquale (2008), citing recent studies,
recommends a minimum protein intake of 2.2 g/kg "for anyone
involved in competitive or intense recreational sports who wants to
maximize lean body mass but does not wish to gain weight".
Water and salts
Water is one of the most important nutrients in the sports diet. It
helps eliminate food waste products in the body, regulates body
temperature during activity and helps with digestion. Maintaining
hydration during periods of physical exertion is key to peak
performance. While drinking too much water during activities can
lead to physical discomfort, dehydration in excess of 2% of body
mass (by weight) markedly hinders athletic performance. Additional
carbohydrates and protein before, during, and after exercise
increase time to exhaustion as well as speed recovery. Dosage is
based on work performed, lean body mass, and environmental factors,
especially ambient temperature and humidity. maintaining the right
amount is key.
Carbohydrates
The main fuel used by the body during exercise is carbohydrates,
which is stored in muscle as glycogen—a form of sugar. During
exercise, muscle glycogen reserves can be used up, especially when
activities last longer than 90 min. Because the amount of
glycogen stored in the body is limited, it is important for
athletes to replace glycogen by consuming a diet high in
carbohydrates. Meeting energy needs can help improve performance
during the sport, as well as improve overall strength and
endurance.
There are different kinds of carbohydrates—simple or refined, and
unrefined. A typical American consumes about 50% of their
carbohydrates as simple sugars, which are added to foods as opposed
to sugars that come naturally in fruits and vegetables. These
simple sugars come in large amounts in sodas and fast food. Over
the course of a year, the average American consumes 54 gallons of
soft drinks, which contain the highest amount of added sugars. Even
though carbohydrates are necessary for humans to function, they are
not all equally healthful. When machinery has been used to remove
bits of high fiber, the carbohydrates are refined. These are the
carbohydrates found in white bread and fast food.
Malnutrition
Malnutrition refers to insufficient, excessive, or imbalanced
consumption of nutrients. In developed countries, the diseases of
malnutrition are most often associated with nutritional imbalances
or excessive consumption.Although there are more people in the
world who are malnourished due to excessive consumption, according
to the United Nations
World
Health Organization, the real challenge in developing nations
today, more than starvation, is combating insufficient nutrition —
the lack of nutrients necessary for the growth and maintenance of
vital functions.
Illnesses caused by improper nutrient consumption
| Nutrients |
Deficiency |
Excess |
| Energy |
Starvation, Marasmus |
Obesity, diabetes mellitus, Cardiovascular disease |
| Simple carbohydrates |
none |
diabetes mellitus, Obesity |
| Complex carbohydrates |
none |
Obesity |
| Saturated fat |
low sex hormone levels |
Cardiovascular disease
(claimed by most doctors and nutritionists) |
| Trans fat |
none |
Cardiovascular
Disease |
| Unsaturated fat |
none |
Obesity |
| Fat |
Malabsorption of Fat-soluble vitamins, Rabbit Starvation (If protein intake is
high) |
Cardiovascular Disease
(claimed by some) |
| Omega 3 Fats |
Cardiovascular
Disease |
Bleeding, Hemorrhages |
| Omega 6 Fats |
none |
Cardiovascular Disease,
Cancer |
| Cholesterol |
none |
Cardiovascular disease
(claimed by many) |
| Protein |
kwashiorkor |
Rabbit starvation |
| Sodium |
hyponatremia |
Hypernatremia, hypertension |
| Iron |
Anemia |
Cirrhosis, heart disease |
| Iodine |
Goiter, hypothyroidism |
Iodine Toxicity (goiter,
hypothyroidism) |
| Vitamin A |
Xerophthalmia and Night Blindness,
low testosterone levels |
Hypervitaminosis A
(cirrhosis, hair loss) |
| Vitamin B1 |
Beri-Beri |
|
| Vitamin B2 |
Cracking of skin and Corneal Unclearation |
|
| Niacin |
Pellagra |
dyspepsia, cardiac arrhythmias, birth defects |
| Vitamin B12 |
Pernicious Anemia |
|
| Vitamin C |
Scurvy |
diarrhea causing dehydration |
| Vitamin D |
Rickets |
Hypervitaminosis D
(dehydration, vomiting, constipation) |
| Vitamin E |
nervous disorders |
Hypervitaminosis E
(anticoagulant: excessive bleeding) |
| Vitamin K |
Hemorrhage |
|
| Calcium |
Osteoporosis, tetany, carpopedal spasm, laryngospasm, cardiac arrhythmias |
Fatigue, depression, confusion, anorexia, nausea,
vomiting, constipation, pancreatitis, increased
urination |
| Magnesium |
Hypertension |
Weakness, nausea, vomiting, impaired breathing, and hypotension |
| Potassium |
Hypokalemia, cardiac arrhythmias |
Hyperkalemia, palpitations |
Mental agility
Research indicates that improving the awareness of nutritious meal
choices and establishing long-term habits of healthy eating has a
positive effect on a cognitive and spatial memory capacity,
potentially increasing a student's potential to process and retain
academic information.
Some organizations have begun working with teachers, policymakers,
and managed foodservice contractors to mandate improved nutritional
content and increased nutritional resources in school cafeterias
from primary to university level institutions. Health and nutrition
have been proven to have close links with overall educational
success. Currently less than 10% of American college students
report that they eat the recommended five servings of fruit and
vegetables daily. Better nutrition has been shown to have an impact
on both cognitive and spatial memory performance; a study showed
those with higher blood sugar levels performed better on certain
memory tests. In another study, those who consumed yogurt performed
better on thinking tasks when compared to those who consumed
caffeine free diet soda or confections. Nutritional deficiencies
have been shown to have a negative effect on learning behavior in
mice as far back as 1951.
- "Better learning performance is associated with diet induced
effects on learning and memory ability".
The "nutrition-learning nexus" demonstrates the correlation between
diet and learning and has application in a higher education
setting.
- "We find that better nourished children perform significantly
better in school, partly because they enter school earlier and thus
have more time to learn but mostly because of greater learning
productivity per year of schooling."
- 91% of college students feel that they are in good health while
only 7% eat their recommended daily allowance of fruits and
vegetables.
- Nutritional education is an effective and workable model in a
higher education setting.
- More "engaged" learning models that encompass nutrition is an
idea that is picking up steam at all levels of the learning
cycle.
There is limited research available that directly links a student's
Grade Point Average (G.P.A.) to their overall nutritional health.
Additional substantive data is needed to prove that overall
intellectual health is closely linked to a person's diet, rather
than just another
correlation
fallacy.
Mental disorders
Nutritional supplement treatment may be appropriate for major
depression,
bipolar disorder,
schizophrenia, and
obsessive compulsive disorder,
the four most common mental disorders in developed countries.
Supplements that have been studied most for mood elevation and
stabilization include
eicosapentaenoic acid and
docosahexaenoic acid (each of which are
an
omega-3 fatty acid contained
in
fish oil, but not in
flaxseed oil),
vitamin
B12,
folic acid, and
inositol.
Cancer
Cancer is now common in developing countries. According a study by
the
International Agency
for Research on Cancer, "In the developing world, cancers of
the liver, stomach and esophagus were more common, often linked to
consumption of carcinogenic preserved foods, such as smoked or
salted food, and parasitic infections that attack organs." Lung
cancer rates are rising rapidly in poorer nations because of
increased use of tobacco. Developed countries "tended to have
cancers linked to affluence or a 'Western lifestyle' — cancers of
the colon, rectum, breast and prostate — that can be caused by
obesity, lack of exercise, diet and age."
Metabolic syndrome
Several lines of evidence indicate lifestyle-induced
hyperinsulinemia and reduced insulin
function (i.e.
insulin
resistance) as a decisive factor in many disease states. For
example, hyperinsulinemia and insulin resistance are strongly
linked to chronic inflammation, which in turn is strongly linked to
a variety of adverse developments such as arterial microinjuries
and
clot formation (i.e. heart disease) and
exaggerated cell division (i.e. cancer). Hyperinsulinemia and
insulin resistance (the so-called
metabolic syndrome) are characterized by
a combination of abdominal
obesity, elevated
blood sugar, elevated
blood pressure, elevated blood
triglycerides, and reduced HDL
cholesterol. The negative impact of
hyperinsulinemia on prostaglandin PGE1/PGE2 balance may be
significant.
The state of
obesity clearly contributes to
insulin resistance, which in turn can cause
type 2 diabetes. Virtually all obese and
most type 2 diabetic individuals have marked insulin resistance.
Although the association between overweight and insulin resistance
is clear, the exact (likely multifarious) causes of insulin
resistance remain less clear. Importantly, it has been demonstrated
that appropriate exercise, more regular food intake and reducing
glycemic load (see below) all can
reverse insulin resistance in overweight individuals (and thereby
lower blood sugar levels in those who have type 2 diabetes).
Obesity can unfavourably alter hormonal and metabolic status via
resistance to the hormone
leptin, and a
vicious cycle may occur in which insulin/leptin resistance and
obesity aggravate one another. The vicious cycle is putatively
fuelled by continuously high insulin/leptin stimulation and fat
storage, as a result of high intake of strongly insulin/leptin
stimulating foods and energy. Both insulin and leptin normally
function as satiety signals to the
hypothalamus in the brain; however,
insulin/leptin resistance may reduce this signal and therefore
allow continued overfeeding despite large body fat stores. In
addition, reduced leptin signalling to the brain may reduce
leptin's normal effect to maintain an appropriately high metabolic
rate.
There is a debate about how and to what extent different dietary
factors— such as intake of processed carbohydrates, total protein,
fat, and carbohydrate intake, intake of saturated and trans fatty
acids, and low intake of vitamins/minerals—contribute to the
development of insulin and leptin resistance. In any case,
analogous to the way modern man-made pollution may potentially
overwhelm the environment's ability to maintain
homeostasis, the recent explosive introduction
of high
glycemic index and processed
foods into the human diet may potentially overwhelm the body's
ability to maintain homeostasis and health (as evidenced by the
metabolic syndrome epidemic).
Hyponatremia
Excess water intake, without replenishment of sodium and potassium
salts, leads to
hyponatremia, which can
further lead to
water
intoxication at more dangerous levels. A well-publicized case
occurred in 2007, when
Jennifer Strange died
while participating in a water-drinking contest. More usually, the
condition occurs in long-distance endurance events (such as
marathon or
triathlon competition and training) and causes
gradual mental dulling, headache, drowsiness, weakness, and
confusion; extreme cases may result in coma, convulsions, and
death. The primary damage comes from swelling of the brain, caused
by increased osmosis as blood salinity decreases.Effective fluid
replacement techniques include Water aid stations during
running/cycling races, trainers providing water during team games
such as Soccer and devices such as Camel Baks which can provide
water for a person without making it too hard to drink the
water.
Processed foods
Since the
Industrial
Revolution some two hundred years ago, the food processing
industry has invented many
technologies
that both help keep foods fresh longer and alter the fresh state of
food as they appear in nature. Cooling is the primary technology
used to maintain freshness, whereas many more technologies have
been invented to allow foods to last longer without becoming
spoiled. These latter technologies include
pasteurisation,
autoclavation,
drying,
salting, and separation of various
components, and all appear to alter the original nutritional
contents of food. Pasteurisation and autoclavation (heating
techniques) have no doubt improved the safety of many common foods,
preventing epidemics of bacterial infection. But some of the (new)
food processing technologies undoubtedly have downfalls as
well.
Modern separation techniques such as
milling,
centrifugation, and
pressing have enabled concentration of particular
components of food, yielding flour, oils, juices and so on, and
even separate fatty acids, amino acids, vitamins, and minerals.
Inevitably, such large scale concentration changes the nutritional
content of food, saving certain nutrients while removing others.
Heating techniques may also reduce food's content of many
heat-labile nutrients such as certain vitamins and phytochemicals,
and possibly other yet to be discovered substances. Because of
reduced nutritional value, processed foods are often 'enriched' or
'fortified' with some of the most critical nutrients (usually
certain vitamins) that were lost during processing. Nonetheless,
processed foods tend to have an inferior nutritional profile
compared to whole, fresh foods, regarding content of both sugar and
high GI starches,
potassium/
sodium, vitamins, fiber, and of intact, unoxidized
(essential) fatty acids. In addition,processed foods often contain
potentially harmful substances such as oxidized fats and trans
fatty acids.
A dramatic example of the effect of food processing on a
population's health is the history of epidemics of
beri-beri in people subsisting on polished rice.
Removing the outer layer of rice by polishing it removes with it
the essential vitamin
thiamine, causing
beri-beri. Another example is the development of
scurvy among infants in the late 1800s in the United
States. It turned out that the vast majority of sufferers were
being fed milk that had been heat-treated (as suggested by
Pasteur) to control bacterial disease.
Pasteurisation was effective against bacteria, but it destroyed the
vitamin C.
As mentioned, lifestyle- and obesity-related diseases are becoming
increasingly prevalent all around the world. There is little doubt
that the increasingly widespread application of some modern food
processing technologies has contributed to this development. The
food processing industry is a major part of modern economy, and as
such it is influential in political decisions (e.g. nutritional
recommendations, agricultural subsidising). In any known
profit-driven economy, health considerations are hardly a priority;
effective production of cheap foods with a long shelf-life is more
the trend. In general, whole, fresh foods have a relatively short
shelf-life and are less profitable to produce and sell than are
more processed foods. Thus the consumer is left with the choice
between more expensive but nutritionally superior whole, fresh
foods, and cheap, usually nutritionally inferior processed foods.
Because processed foods are often cheaper, more convenient (in both
purchasing, storage, and preparation), and more available, the
consumption of nutritionally inferior foods has been increasing
throughout the world along with many nutrition-related health
complications.
History
Humans have evolved as
omnivorous hunter-gatherers over the past 250,000
years. The diet of early modern humans varied significantly
depending on location and climate. The diet in the tropics tended
to be based more heavily on plant foods, while the diet at higher
latitudes tended more towards animal products. Analysis of
postcranial and cranial remains of humans and animals from the
Neolithic, along with detailed bone modification studies have shown
that cannibalism was also prevalent among prehistoric humans.
Agriculture developed about 10,000 years
ago in multiple locations throughout the world, providing grains
such as
wheat,
rice,
potatoes, and
maize,
with staples such as
bread,
pasta, and
tortillas. Farming
also provided milk and dairy products, and sharply increased the
availability of meats and the diversity of vegetables. The
importance of food purity was recognized when bulk storage led to
infestation and contamination risks.
Cooking
developed as an often ritualistic activity, due to efficiency and
reliability concerns requiring adherence to strict recipes and
procedures, and in response to demands for food purity and
consistency.
From antiquity to 1900
The first recorded nutritional experiment is found in the Bible's
Book of Daniel.
Daniel and his friends
were captured by the king of Babylon
during an
invasion of Israel. Selected as court servants, they were to
share in the king's fine foods and wine. But they objected,
preferring vegetables (
pulses) and
water in accordance with their
Jewish dietary
restrictions. The king's chief steward reluctantly agreed to a
trial. Daniel and his friends received their diet for 10 days and
were then compared to the king's men. Appearing healthier, they
were allowed to continue with their diet.

Anaxagoras
Around 475 BC,
Anaxagoras stated that
food is absorbed by the human body and therefore contained
"homeomerics" (generative components), suggesting the existence of
nutrients. Around 400 BC,
Hippocrates
said, "Let food be your medicine and medicine be your food."
In the 1500s, scientist and artist
Leonardo da Vinci compared
metabolism to a burning candle. In 1747, Dr.
James Lind, a physician in the British
navy, performed the first
scientific
nutrition experiment, discovering that
lime juice saved sailors who had been at sea
for years from
scurvy, a deadly and painful
bleeding disorder. The discovery was ignored for forty years, after
which British sailors became known as "limeys." The essential
vitamin C within lime juice would not be
identified by scientists until the 1930s.
Around 1770,
Antoine Lavoisier,
the "Father of Nutrition and Chemistry" discovered the details of
metabolism, demonstrating that the
oxidation of food is the source of body heat. In
1790,
George Fordyce recognized
calcium as necessary for fowl survival. In
the early 1800s, the elements
carbon,
nitrogen,
hydrogen
and
oxygen were recognized as the primary
components of food, and methods to measure their proportions were
developed.
In 1816,
François Magendie
discovered that dogs fed only
carbohydrates and
fat lost
their body
protein and died in a few weeks,
but dogs also fed protein survived, identifying protein as an
essential dietary component. In 1840,
Justus Liebig discovered the chemical makeup
of carbohydrates (
sugars), fats (
fatty acids) and proteins (
amino acids.) In the 1860s,
Claude Bernard discovered that body fat can
be synthesized from carbohydrate and protein, showing that the
energy in blood
glucose can be stored as fat
or as
glycogen.
In the early 1880s,
Kanehiro Takaki
observed that Japanese sailors (whose diets consisted almost
entirely of white rice) developed
beriberi
(or endemic neuritis, a disease causing heart problems and
paralysis) but British sailors and Japanese naval officers did not.
Adding various types of vegetables and meats to the diets of
Japanese sailors prevented the disease.
In 1896, Baumann observed
iodine in thyroid
glands.
In
1897, Christiaan Eijkman worked
with natives of Java
, who also
suffered from beriberi. Eijkman observed that chickens fed
the native diet of white rice developed the symptoms of beriberi,
but remained healthy when fed unprocessed brown rice with the outer
bran intact. Eijkman cured the natives by feeding them brown rice,
discovering that food can cure disease. Over two decades later,
nutritionists learned that the outer rice bran contains vitamin B1,
also known as
thiamine.
From 1900 to the present
In the early 1900s,
Carl Von Voit and
Max Rubner independently measured
caloric energy expenditure in different
species of animals, applying principles of physics in nutrition. In
1906, Wilcock and Hopkins showed that the amino acid
tryptophan was necessary for the survival of
rats. He fed them a special mixture of food containing all the
nutrients he believed were essential for survival, but the rats
died. A second group of rats to which he also fed fed an amount of
milk containing
vitamins.
Gowland Hopkins recognized "accessory food
factors" other than calories, protein and
minerals, as
organic materials essential to health but
which the body cannot synthesize. In 1907,
Stephen M. Babcock and
Edwin B. Hart
conducted the
single-grain
experiment. This experiment runs through 1911.
In 1912,
Casimir Funk coined the term
vitamin, a vital factor in the diet, from
the words "vital" and "amine," because these unknown substances
preventing scurvy, beriberi, and
pellagra,
were thought then to be derived from ammonia. The vitamins were
studied in the first half of the twentieth century.
In 1913,
Elmer McCollum discovered
the first vitamins, fat soluble
vitamin A,
and water soluble
vitamin B (in 1915; now
known to be a complex of several water-soluble vitamins) and names
vitamin C as the then-unknown substance
preventing scurvy.
Lafayette Mendel
and Thomas Osborne also perform pioneering work on vitamin A and B.
In 1919, Sir
Edward Mellanby
incorrectly identified
rickets as a vitamin
A deficiency, because he could cure it in dogs with cod liver oil.
In 1922, McCollum destroyed the vitamin A in cod liver oil but
finds it still cures rickets, naming
vitamin
D Also in 1922, H.M. Evans and L.S. Bishop discover
vitamin E as essential for rat pregnancy,
originally calling it "food factor X" until 1925.
In 1925, Hart discovered that trace amounts of
copper are necessary for
iron
absorption. In 1927,
Adolf
Otto Reinhold Windaus synthesized vitamin D, for which he won
the
Nobel Prize in Chemistry in 1928. In
1928,
Albert Szent-Györgyi
isolated
ascorbic acid, and in 1932
proves that it is vitamin C by preventing scurvy. In 1935 he
synthesizes it, and in 1937 he wins a Nobel Prize for his efforts.
Szent-Györgyi concurrently elucidates much of the
citric acid cycle.
In the 1930s,
William Cumming
Rose identified
essential amino
acids, necessary protein components which the body cannot
synthesize. In 1935, Underwood and Marston independently discover
the necessity of
cobalt. In 1936,
Eugene Floyd Dubois showed that work and
school performance are related to caloric intake. In 1938,
Erhard Fernholz discovered the chemical
structure of vitamin E. It was synthesised by
Paul Karrer.
In 1940,
rationing
in the United Kingdom during and after World War II took place
according to nutritional principles drawn up by
Elsie Widdowson and others. In 1941, the
first
Recommended Dietary
Allowances (RDAs) were established by the
National Research
Council.
In 1992, The U.S. Department of Agriculture introduced the
Food Guide Pyramid. In 2002, a
Natural Justice study showed a relation
between nutrition and violent behavior. In 2005, a study found that
obesity may be caused by
adenovirus in
addition to bad nutrition.
See also
Balanced
Eating:
Biology:
Dangers of poor nutrition
Food:
|
Healthy diet:
Lists:
Nutrients:
|
Profession:
Tools:
Organizations:
Related topics
|
Further reading
- Curley, S., and Mark (1990). The Natural Guide to Good
Health, Lafayette, Louisiana, Supreme Publishing
References
External links
Databases and search engines