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Venkatraman "Venki" Ramakrishnan ( ; born 1952 in Chidambarammarker, Tamil Nadumarker, Indiamarker) is a structural biologist at the MRC Laboratory of Molecular Biologymarker in Cambridge, Englandmarker. He received the 2009 Nobel Prize in Chemistry "for studies of the structure and function of the ribosome".

Early life

Venkatraman Ramakrishnan was born in Chidambarammarker in Cuddalore district of Tamil Nadumarker, Indiamarker.

He moved to Baroda (Vadodaramarker) in Gujaratmarker state at the age of three, where he had his schooling, except for spending 1960–61 in Adelaidemarker, Australia. Following his Pre-Science at the Maharaja Sayajirao University of Barodamarker, he did his undergraduate studies in the same university on a National Science Talent Scholarship, graduating with a B.Sc. in Physics in 1971. Immediately after graduation he moved to the U.S.A., where he obtained his Ph.D. in Physics from Ohio Universitymarker in 1976. He then spent two years studying biology as a graduate student at the University of California, San Diegomarker while making a transition from theoretical physics to biology.

Career

Ramakrishnan first began work on ribosomes as a postdoctoral fellow with Peter Moore at Yale.. He continued to work on ribosomes as a staff scientist at Brookhaven National Laboratorymarker. In 1995 he moved to the University of Utah as a Professor of Biochemistry, and in 1999, he moved to his current position at the Medical Research Council Laboratory of Molecular Biologymarker in Cambridgemarker, England.

In 1999, Ramakrishnan's laboratory published a 5.5 Angstrom resolution structure of the 30S subunit. The following year, his laboratory determined the complete atomic structure of the 30S subunit of the ribosome and its complexes with several antibiotics. This was followed by studies that provided structural insights into the mechanism that ensures the fidelity of protein biosynthesis. More recently, his laboratory has determined the atomic structure of the whole ribosome in complex with its tRNA and mRNA ligands. Ramakrishnan is also known for his past work on histone and chromatin structure.

Honours

Ramakrishnan is a Fellow of the Royal Society, a member of EMBO and the U.S. National Academy of Sciencesmarker and a Fellow of Trinity College, Cambridgemarker. He was awarded the 2007 Louis-Jeantet Prize for Medicine, the 2008 Heatley Medal of the British Biochemical Society and the 2009 Rolf-Sammet Professorship at the University of Frankfurt. In 2009, Ramakrishnan was awarded the Nobel Prize in Chemistry along with Thomas A. Steitz and Ada Yonath.

Personal life

Ramakrishnan is married to Vera Rosenberry, an author and illustrator of children's books. He has a stepdaughter, Tanya Kapka, who is a doctor in Oregon, and a son, Raman Ramakrishnan, who is a cellist based in New York who plays with the Daedalus Quartet.

Publications

A full list of publications can be found here

References

External links




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